A warrant was executed by officers at 5pm on Saturday at an address in Priory Road, Clacton.
According to Essex Police, about 100 cannabis plants were found across four rooms.
Mattresses were also on the floor of the kitchen.
Three men, aged 25, 27 and 32, who were at the property at the time, were arrested on suspicion of being concerned in the production of cannabis.
They remain in custody for questioning.